Could the QTc prolongation seen in diabetic ketoacidosis be due to more than just a raised anion gap?








By: Rebecca Clarke, Adam Ioannou

Posted on: December 14, 2020



Could the QTc prolongation seen in diabetic ketoacidosis be due to more than just a raised anion gap?



Perez et al [1] demonstrated that nearly one third of patients presenting with diabetic ketoacidosis (DKA) had QTc prolongation. The authors demonstrated a significant correlation between the QTc and anion gap, and therefore hypothesised that the QTc prolongation seen was secondary to an elevated anion gap and metabolic acidosis.



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