Researchers create gene expression database to gain new insights into pneumococcal infections

Posted on: December 15, 2020

Researchers create gene expression database to gain new insights into pneumococcal infections

Researchers at the University of Maryland School of Medicine published one of the most comprehensive analyses of how genes get expressed during infection (known as a transcriptome). The analyses include three different strains of the bacteria Streptococcus pneumoniae, which causes pneumonia, meningitis and middle-ear infections. It also includes analyses of the lungs and four other organs in an animal model where the bacteria resides, multiplies and takes hold in the body. Their findings were published today in the Proceedings of the National Academy of Sciences.